Robert Farago at The Truth About Guns makes a great point: if you're going to rely on a gun for home defense, you need to have a gun in reach at all times. And that means carrying one in the home.

Remember: that bump-in-the-night I’ll get my gun out of the safe or grab the one by my bed scenario that most people like to prepare? It’s only one possibility of many. Unless you’re home carrying, you are only ready for a very specific set of circumstances.

I pretty much always have at least a P3AT in my pocket or within my wingspan. The only exception is when I'm in the shower.